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Moreover, after inhibition of Sat1, compared to AAV9-sh-Scr + MIRI group, increased TFR1 protein expression and decreased GPX4 protein expression were obviously reversed in AAV9-sh-Sat1+MIRI group (Figures 3JM)

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Insulin/IGF-1 signaling: multiple STAT3-related downstream pathways InsR/IGF-1R activate JAK-STAT3 signaling The InsR and IGF-1R proteins are receptor tyrosine kinases (RTK) and thus they are members of the tyrosine kinase superfamily

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