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10.1016/j.tox.2016.08.016 118 Pogrmic-MajkicK.SamardzijaD.Stojkov-MimicN.VukosavljevicJ.Trninic-PjevicA.KopitovicV.et al (2018)

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This section summarizes the most influential clinical trials in immunotherapy and cell/gene-based approaches for type 1 diabetes (T1D), with particular emphasis on their reported efficacy and the remaining feasibility challenges

Body composition outcomes were studied by a handful of mouse models utilizing cell-specific promoters driving ARKO within SCs [191, 192, 203], myoblasts [183, 204], myocytes [187, 205,206,207,208], myofibers [183, 204, 209], neurons [192, 210, 211], osteoblasts [212,213,214], osteoclasts [182], and adipose [215, 216]