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The pattern of early TR expression, followed by expression of TR, is seen across all species studied including Xenopus , chick, as well as in mammalian development

However, the overall anti-inflammatory effect was more pronounced in seal cells, which also downregulated additional cell-proliferation signalling pathways (Transforming Growth Factor [TGF-] and Nuclear Factor [NF-kB]) (Figure 1)

Beta-oxidation of these fatty acids in mitochondria generates reactive oxygen species (ROS) as a normal byproduct

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